HCID 59631194, compound → HCID 59631274, compound

HRID 1431459Notes

Reaction equation

HRID 1431459 reaction equation
[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[NH:9][C:10](=[O:18])[CH:11]([CH3:17])[C:12]([O:14]CC)=[O:13]>C1COCC1>[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[NH:9][C:10](=[O:18])[CH:11]([CH3:17])[C:12]([OH:14])=[O:13]

Participants

3

Reactant 1

HCID 59631194HCID 59631194, compound

Product 1

HCID 59631274HCID 59631274, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

The acid was prepared according to Procedure B using ethyl 3-(2,4-difluorophenylamino)-2-methyl-3-oxopropanoate (5.1 g, 19.83 mmol) in THF (19.8 mL) to give 3-(2,4-difluorophenylamino)-2-methyl-3-oxopropanoic acid. Mass Spectrum (ESI) m/e=230.1 (M+1).

Workup

  1. customThe acid was prepared

Sources & evidence

ORD record
ord-5132c6000cf14143a58a71f48957fa0e
Source dataset
uspto-grants-2015_01
Patent number
US08940724B2

Reaction notes

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