Ethyl 3-(2-chloro-3-fluorophenylamino)-2-methyl-3-oxopropanoate → HCID 59631084, compound

HRID 1431463Notes

Reaction equation

HRID 1431463 reaction equation
[Cl:1][C:2]1[C:7]([F:8])=[CH:6][CH:5]=[CH:4][C:3]=1[NH:9][C:10](=[O:18])[CH:11]([CH3:17])[C:12]([O:14]CC)=[O:13]>C1COCC1>[Cl:1][C:2]1[C:7]([F:8])=[CH:6][CH:5]=[CH:4][C:3]=1[NH:9][C:10](=[O:18])[CH:11]([CH3:17])[C:12]([OH:14])=[O:13]

Participants

3

Reactant 1

HCID 59631446Ethyl 3-(2-chloro-3-fluorophenylamino)-2-methyl-3-oxopropanoate

Product 1

HCID 59631084HCID 59631084, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

The acid was prepared according to Procedure B using ethyl 3-(2-chloro-3-fluorophenylamino)-2-methyl-3-oxopropanoate (5.0 g, 18.27 mmol) in THF (18.3 mL) to give 3-(2-chloro-3-fluorophenylamino)-2-methyl-3-oxopropanoic acid. Mass Spectrum (ESI) m/e=245.9 (M+1).

Workup

  1. customThe acid was prepared

Sources & evidence

ORD record
ord-350e52c4b85141578c6642e070b7d04a
Source dataset
uspto-grants-2015_01
Patent number
US08940724B2

Reaction notes

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