HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 3-(2-chloro-3,5-difluorophenylamino)-2-methyl-3-oxopropanoate → 3-(2-Chloro-3,5-difluorophenylamino)-2-methyl-3-oxopropanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 3-(2-chloro-3,5-difluorophenylamino)-2-methyl-3-oxopropanoate | HCID 59631036 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-(2-Chloro-3,5-difluorophenylamino)-2-methyl-3-oxopropanoic acid | HCID 59631319 | — |
Reaction Steps
The acid was prepared according to Procedure B using ethyl 3-(2-chloro-3,5-difluorophenylamino)-2-methyl-3-oxopropanoate (5.0 g, 17.14 mmol) in THF (17.1 mL) to give 3-(2-chloro-3,5-difluorophenylamino)-2-methyl-3-oxopropanoic acid. Mass Spectrum (ESI) m/e=264.0 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08940724B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-c35a801a14a540b7beb5c6d04579fa85 |
| Source note | uspto-grants-2015_01 |