HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine → 4-(4-Chloro-5,7-difluoro-3-methylquinolin-2-yl)morpholine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | 4-Chloro-5,7-difluoro-3-methyl-2-(2-(methylsulfonyl)phenyl)quinoline | HCID 59631037 | — |
| Product | 4-(4-Chloro-5,7-difluoro-3-methylquinolin-2-yl)morpholine | HCID 59631060 | — |
Reaction Steps
Essentially prepared according to Procedure G using 4-chloro-5,7-difluoro-3-methyl-2-(2-(methylsulfonyl)phenyl)quinoline (380.0 mg, 1.50 mmol) and morpholine to give 4-(4-chloro-5,7-difluoro-3-methylquinolin-2-yl)morpholine. Mass Spectrum (ESI) m/e=299.0 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08940724B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-be764f89e70d4993a8cff576c587117c |
| Source note | uspto-grants-2015_01 |