Hydrogen Bromide → HCID 68615631, compound

HRID 1431974Notes

Reaction equation

HRID 1431974 reaction equation
[CH2:1]1[O:9][C:8]2[CH:7]=[CH:6][C:5]([C:10]([C:12]#[C:13][CH2:14][NH:15][S:16]([C:19]3[CH:24]=[CH:23][CH:22]=[C:21]([Cl:25])[CH:20]=3)(=[O:18])=[O:17])=O)=[CH:4][C:3]=2[O:2]1.[BrH:26]>C(O)(=O)C>[Br:26][C:13]1[CH:12]=[C:10]([C:5]2[CH:6]=[CH:7][C:8]3[O:9][CH2:1][O:2][C:3]=3[CH:4]=2)[N:15]([S:16]([C:19]2[CH:24]=[CH:23][CH:22]=[C:21]([Cl:25])[CH:20]=2)(=[O:18])=[O:17])[CH:14]=1

Participants

4

Reactant 2

HCID 260Hydrogen BromideHCID 131727711HCID 131727711, compound

Product 1

HCID 68615631HCID 68615631, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

The title compound is prepared from 3-(m-chlorobenzenesulfonylamino)-1-propinyl 3,4-methylenedioxyphenyl ketone and HBr in acetic acid following the procedure of Example 3b. 1H-NMR (300 MHz, CDCl3): 7.6-7.5 (m, 1H); 7.54 (d, J=2.0 Hz, 1H); 7.4-7.3 (m, 3H); 6.8-6.7 (m, 1H); 6.7-6.6 (m, 2H); 6.16 (d, J=2.0 Hz, 1H); 6.05 (s, 2H).

Sources & evidence

ORD record
ord-3246d82b0899468584d29fee3f113a34
Source dataset
uspto-grants-2009_11
Patent number
US07612064B2

Reaction notes

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