HCID 68547156, compound → HCID 68546525, compound

Participants

Reaction Steps

A solution of 183 mg (0.37 mmol) [(3S,6S,14R,16S)-3,14-dimethyl-16-((2S,4R)-4-methyl-5-oxo-tetrahydro-furan-2-yl)-2,5-dioxo-1,4diaza-cyclohexadec-10-en-6-yl]-carbamic acid tert-butyl ester in 1.5 ml butylamine is heated to 65° C. under nitrogen for two hours. The reaction mixture is evaporated, the residue taken up in toluene and evaporated to dryness to yield the title compound.

Provenance & Evidence