HCID 68544807, compound → HCID 68544322, compound

Participants

Reaction Steps

A solution of 16-methoxy-9-methyl-11-(4-methyl-5-oxo-tetrahydro-furan-2-yl)-2,12,17-triaza-bicyclo[12.3.1]octadeca-1(17),14(18),15-trien-13-one (49 mg, 0.12 mmol) in 1.2 ml butylamine is stirred at 50° for 3 h. Excess butylamine is evaporated and the residue purified by chromatography on silica gel to afford the title compound (mixture of diastereomers) as a slightly yellow powder.

Provenance & Evidence