Cyclohexanepropionaldehyde → HCID 69069591, compound

HRID 1432440Notes

Reaction equation

HRID 1432440 reaction equation
[CH:1]1([CH2:7][CH2:8][CH:9]=[O:10])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:11][O:12][C:13](=O)/[CH:14]=[CH:15]/[O:16]C>>[CH:1]1([CH2:7][CH2:8][CH:9]2[O:10][C:15](=[O:16])[CH:14]=[C:13]2[O:12][CH3:11])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 78070CyclohexanepropionaldehydeHCID 5323651Methyl 3-methoxyacrylate

Product 1

HCID 69069591HCID 69069591, compound

Procedure

Using general procedure A, cyclohexanepropanal (Stratakis, Manolis et al., Journal of Organic Chemistry (2002), 67(25), 8758-8763) was reacted with 3(E)-methoxy-acrylic acid methyl ester to give rac-5-(2-cyclohexyl-ethyl)-4-methoxy-5H-furan-2-one as a colorless solid. MS: 225.2 ([M+H]+).

Sources & evidence

ORD record
ord-f6e6002dc64e443fa64f08ff0981f062
Source dataset
uspto-grants-2009_11
Patent number
US07612099B2

Reaction notes

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