HRID1432449

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID240

Benzaldehyde

C7H6O

结构：O=S(=O)(NCCc1c[nH]c2ccccc12)c1ccc2ccccc2c1

HCID2737733

未命名化合物

HCID56604111

未命名化合物

PRODUCTS

生成物

结构：CC(C)C1NC(=O)C(C(c2ccccc2)c2[nH]c3ccccc3c2CCNS(=O)(=O)c2ccc3ccccc3c2)=C1O

HCID57933457

未命名化合物

PROCEDURE

实验过程

Using general procedure C, 4-hydroxy-5-isopropyl-1,5-dihydro-pyrrol-2-one (Lit. 11) was reacted with benzaldehyde and naphthalene-2-sulfonic acid [2-(1H-indol-3-yl)-ethyl]-amide (Lit. 1) to give the title compound as an orange solid. MS: 580.3 ([M+H]+).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-87ab5f7b6abf40668f649233e63120a4
来源数据集: uspto-grants-2009_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07612099B2
来源说明: uspto-grants-2009_11

反应 SMILES

[OH:1][C:2]1[CH:6]([CH:7]([CH3:9])[CH3:8])[NH:5][C:4](=[O:10])[CH:3]=1.[CH:11](=O)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1.[NH:19]1[C:27]2[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=2)[C:21]([CH2:28][CH2:29][NH:30][S:31]([C:34]2[CH:43]=[CH:42][C:41]3[C:36](=[CH:37][CH:38]=[CH:39][CH:40]=3)[CH:35]=2)(=[O:33])=[O:32])=[CH:20]1>>[OH:1][C:2]1[CH:6]([CH:7]([CH3:9])[CH3:8])[NH:5][C:4](=[O:10])[C:3]=1[CH:11]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[C:20]1[NH:19][C:27]2[C:22]([C:21]=1[CH2:28][CH2:29][NH:30][S:31]([C:34]1[CH:43]=[CH:42][C:41]3[C:36](=[CH:37][CH:38]=[CH:39][CH:40]=3)[CH:35]=1)(=[O:32])=[O:33])=[CH:23][CH:24]=[CH:25][CH:26]=2