Benzaldehyde → HCID 57933464, compound

HRID 1432451Notes

Reaction equation

HRID 1432451 reaction equation
[OH:1][C:2]1[CH:6]([CH:7]([CH3:9])[CH3:8])[N:5]([CH3:10])[C:4](=[O:11])[CH:3]=1.[CH:12](=O)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.[F:20][C:21]1[CH:22]=[C:23]2[C:27](=[CH:28][CH:29]=1)[NH:26][CH:25]=[C:24]2[CH3:30]>>[F:20][C:21]1[CH:22]=[C:23]2[C:27](=[CH:28][CH:29]=1)[NH:26][C:25]([CH:12]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[C:3]1[C:4](=[O:11])[N:5]([CH3:10])[CH:6]([CH:7]([CH3:9])[CH3:8])[C:2]=1[OH:1])=[C:24]2[CH3:30]

Participants

4

Reactant 3

HCID 240BenzaldehydeHCID 223515035-Fluoro-3-methyl-1H-indoleHCID 69067127HCID 69067127, compound

Product 1

HCID 57933464HCID 57933464, compound

Procedure

Using general procedure C, 4-hydroxy-5-isopropyl-1-methyl-1,5-dihydro-pyrrol-2-one (Lit. 12) was reacted with benzaldehyde and 5-fluoro-3-methyl-1H-indole to give the title compound as a yellow solid. MS: 391.3 ([M−H]−).

Sources & evidence

ORD record
ord-a7917581a1db4ea99f4c9e5e87a98951
Source dataset
uspto-grants-2009_11
Patent number
US07612099B2

Reaction notes

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