Benzaldehyde → HCID 57933446, compound

HRID 1432452Notes

Reaction equation

[OH:1][C:2]1[CH:6]([CH:7]([CH3:9])[CH3:8])[NH:5][C:4](=[O:10])[CH:3]=1.[CH:11](=O)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1.[CH3:19][C:20]1[C:28]2[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=2)[NH:22][CH:21]=1>>[OH:1][C:2]1[CH:6]([CH:7]([CH3:9])[CH3:8])[NH:5][C:4](=[O:10])[C:3]=1[CH:11]([C:21]1[NH:22][C:23]2[C:28]([C:20]=1[CH3:19])=[CH:27][CH:26]=[CH:25][CH:24]=2)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

Participants

Reactant 3

HCID 240Benzaldehyde

HCID 6736Skatole

HCID 566041114-Hydroxy-5-isopropyl-1,5-dihydro-pyrrol-2-one

Product 1

HCID 57933446HCID 57933446, compound

Procedure

Using general procedure C, 4-hydroxy-5-isopropyl-1,5-dihydro-pyrrol-2-one (Lit. 11) was reacted with benzaldehyde and 3-methyl-1H-indole to give the title compound as a yellow solid. MS: 361.0 ([M+H]+).

Sources & evidence

ORD record: ord-1fba9533e2ca413cb09adaa1850bde87
Source dataset: uspto-grants-2009_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07612099B2

Reaction notes

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