Benzaldehyde → HCID 57933483, compound

HRID 1432454Notes

Reaction equation

[OH:1][C:2]1[CH2:6][O:5][C:4](=[O:7])[CH:3]=1.[CH:8](=O)[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1.[NH:16]1[C:24]2[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=2)[C:18]([CH2:25][CH2:26][NH:27][C:28](=[O:30])[CH3:29])=[CH:17]1>>[OH:1][C:2]1[CH2:6][O:5][C:4](=[O:7])[C:3]=1[CH:8]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:17]1[NH:16][C:24]2[C:19]([C:18]=1[CH2:25][CH2:26][NH:27][C:28](=[O:30])[CH3:29])=[CH:20][CH:21]=[CH:22][CH:23]=2

Participants

Reactant 3

HCID 240Benzaldehyde

HCID 70547N-Acetyltryptamine

HCID 546838134-Hydroxyfuran-2(5H)-one

Product 1

HCID 57933483HCID 57933483, compound

Procedure

Using general procedure C, 4-hydroxy-5H-furan-2-one was reacted with benzaldehyde and N-[2-(1H-indol-3-yl)-ethyl]-acetamide to give the title compound as orange foam. MS: 391.1 ([M+H]+).

Sources & evidence

ORD record: ord-0531ae3e530c4727909c425cd5682aac
Source dataset: uspto-grants-2009_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07612099B2

Reaction notes

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