Benzaldehyde → HCID 57933449, compound

HRID 1432465Notes

Reaction equation

HRID 1432465 reaction equation
[CH2:1]([CH:8]1[O:12][C:11](=[O:13])[CH:10]=[C:9]1[OH:14])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH:15](=O)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1.[NH:23]1[C:31]2[C:26](=[CH:27][CH:28]=[CH:29][CH:30]=2)[C:25]([CH2:32][CH2:33][N:34]([CH3:38])[C:35](=[O:37])[CH3:36])=[CH:24]1>>[CH2:1]([CH:8]1[O:12][C:11](=[O:13])[C:10]([CH:15]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[C:24]2[NH:23][C:31]3[C:26]([C:25]=2[CH2:32][CH2:33][N:34]([CH3:38])[C:35](=[O:37])[CH3:36])=[CH:27][CH:28]=[CH:29][CH:30]=3)=[C:9]1[OH:14])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 3

HCID 240BenzaldehydeHCID 383154HCID 383154, compoundHCID 690635555-benzyl-4-hydroxy-5H-furan-2-one

Product 1

HCID 57933449HCID 57933449, compound

Procedure

Using general procedure C, 5-benzyl-4-hydroxy-5H-furan-2-one (Lit. 13) was reacted with benzaldehyde and N-[2-(1H-indol-3-yl)-ethyl]-N-methyl-acetamide (Lit. 4) to give the title compound as pale yellow solid. MS: 493.3 ([M−H]−).

Sources & evidence

ORD record
ord-ee5198873f754e3ca622e36f09d4ae15
Source dataset
uspto-grants-2009_11
Patent number
US07612099B2

Reaction notes

Loading…