Benzaldehyde → HCID 57933414, compound

HRID 1432468Notes

Reaction equation

HRID 1432468 reaction equation
[CH2:1]([CH:8]1[O:12][C:11](=[O:13])[CH:10]=[C:9]1[OH:14])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH:15](=O)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1.[F:23][C:24]1[CH:25]=[C:26]2[C:30](=[CH:31][CH:32]=1)[NH:29][CH:28]=[C:27]2[CH3:33]>>[CH2:1]([CH:8]1[O:12][C:11](=[O:13])[C:10]([CH:15]([C:28]2[NH:29][C:30]3[C:26]([C:27]=2[CH3:33])=[CH:25][C:24]([F:23])=[CH:32][CH:31]=3)[C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)=[C:9]1[OH:14])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 3

HCID 240BenzaldehydeHCID 223515035-Fluoro-3-methyl-1H-indoleHCID 690635555-benzyl-4-hydroxy-5H-furan-2-one

Product 1

HCID 57933414HCID 57933414, compound

Procedure

Using general procedure C, 5-benzyl-4-hydroxy-5H-furan-2-one (Lit. 13) was reacted with benzaldehyde and 5-fluoro-3-methyl-1H-indole to give the title compound as colorless solid. MS: 426.1 ([M−H]−).

Sources & evidence

ORD record
ord-62416999f8474b89a615143a9badc715
Source dataset
uspto-grants-2009_11
Patent number
US07612099B2

Reaction notes

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