Benzaldehyde → HCID 57933480, compound

HRID 1432472Notes

Reaction equation

HRID 1432472 reaction equation
[OH:1][C:2]1[CH:6]([CH2:7][CH:8]([CH3:10])[CH3:9])[O:5][C:4](=[O:11])[CH:3]=1.[CH:12](=O)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.[NH:20]1[C:28]2[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=2)[C:22]([CH2:29][CH2:30][NH:31][C:32](=[O:34])[CH3:33])=[CH:21]1>>[OH:1][C:2]1[CH:6]([CH2:7][CH:8]([CH3:9])[CH3:10])[O:5][C:4](=[O:11])[C:3]=1[CH:12]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[C:21]1[NH:20][C:28]2[C:23]([C:22]=1[CH2:29][CH2:30][NH:31][C:32](=[O:34])[CH3:33])=[CH:24][CH:25]=[CH:26][CH:27]=2

Participants

4

Reactant 3

HCID 240BenzaldehydeHCID 70547N-AcetyltryptamineHCID 69066185HCID 69066185, compound

Product 1

HCID 57933480HCID 57933480, compound

Procedure

Using general procedure C, 4-hydroxy-5-isobutyl-5H-furan-2-one (Lit. 14) was reacted with benzaldehyde and N-[2-(1H-indol-3-yl)-ethyl]-acetamide to give the title compound as a white solid. MS: 441.1 ([M+H]+).

Sources & evidence

ORD record
ord-cc14f5bddc9f411c8304972271519006
Source dataset
uspto-grants-2009_11
Patent number
US07612099B2

Reaction notes

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