Benzaldehyde → HCID 57933421, compound

HRID 1432473Notes

Reaction equation

HRID 1432473 reaction equation
[OH:1][C:2]1[C:6]2([CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]2)[O:5][C:4](=[O:12])[CH:3]=1.[CH:13](=O)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1.[NH:21]1[C:29]2[C:24](=[CH:25][CH:26]=[CH:27][CH:28]=2)[C:23]([CH2:30][CH2:31][NH:32][C:33](=[O:35])[CH3:34])=[CH:22]1>>[OH:1][C:2]1[C:6]2([CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]2)[O:5][C:4](=[O:12])[C:3]=1[CH:13]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[C:22]1[NH:21][C:29]2[C:24]([C:23]=1[CH2:30][CH2:31][NH:32][C:33](=[O:35])[CH3:34])=[CH:25][CH:26]=[CH:27][CH:28]=2

Participants

4

Reactant 3

HCID 240BenzaldehydeHCID 70547N-AcetyltryptamineHCID 54717027HCID 54717027, compound

Product 1

HCID 57933421HCID 57933421, compound

Procedure

Using general procedure C, 4-hydroxy-1-oxa-spiro[4.5]dec-3-en-2-one (Lit. 15) was reacted with benzaldehyde and N-[2-(1H-indol-3-yl)-ethyl]-acetamide to give the title compound as a white solid. MS: 459.1 ([M+H]+).

Sources & evidence

ORD record
ord-1ab532b6aa1b4405a09a7d2baf4cf538
Source dataset
uspto-grants-2009_11
Patent number
US07612099B2

Reaction notes

Loading…