Benzaldehyde → HCID 57933468, compound

HRID 1432492Notes

Reaction equation

HRID 1432492 reaction equation
[OH:1][C:2]1[CH:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[CH2:5][C:4](=[O:13])[CH:3]=1.[CH:14](=O)[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1.[CH3:22][O:23][C:24]1[CH:32]=[C:31]2[C:27]([C:28]([CH2:33][CH2:34][NH:35][C:36](=[O:38])[CH3:37])=[CH:29][NH:30]2)=[CH:26][CH:25]=1>>[OH:1][C:2]1[CH:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[CH2:5][C:4](=[O:13])[C:3]=1[CH:14]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)[C:29]1[NH:30][C:31]2[C:27]([C:28]=1[CH2:33][CH2:34][NH:35][C:36](=[O:38])[CH3:37])=[CH:26][CH:25]=[C:24]([O:23][CH3:22])[CH:32]=2

Participants

4

Reactant 3

HCID 240BenzaldehydeHCID 1785786HCID 1785786, compoundHCID 690696643-Hydroxy-4-phenyl-cyclopent-2-enone

Product 1

HCID 57933468HCID 57933468, compound

Procedure

Using general procedure C, 3-hydroxy-4-phenyl-cyclopent-2-enone (Lit. 17) was reacted with benzaldehyde and N-[2-(6-methoxy-1H-indol-3-yl)-ethyl]-acetamide (Lit. 7) to give the title compound as a pale red solid. MS: 495.5 ([M+H]+).

Sources & evidence

ORD record
ord-370c4ff4d94a451eb1865dcff264c988
Source dataset
uspto-grants-2009_11
Patent number
US07612099B2

Reaction notes

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