Benzaldehyde → HCID 57933432, compound

HRID 1432510Notes

Reaction equation

HRID 1432510 reaction equation
[OH:1][C:2]1[CH:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[CH2:5][C:4](=[O:13])[CH:3]=1.[CH:14](=O)[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1.[F:22][C:23]1[CH:24]=[C:25]2[C:29](=[CH:30][CH:31]=1)[NH:28][CH:27]=[C:26]2[CH3:32]>>[F:22][C:23]1[CH:24]=[C:25]2[C:29](=[CH:30][CH:31]=1)[NH:28][C:27]([CH:14]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)[C:3]1[C:4](=[O:13])[CH2:5][CH:6]([C:7]3[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=3)[C:2]=1[OH:1])=[C:26]2[CH3:32]

Participants

4

Reactant 3

HCID 240BenzaldehydeHCID 223515035-Fluoro-3-methyl-1H-indoleHCID 690696643-Hydroxy-4-phenyl-cyclopent-2-enone

Product 1

HCID 57933432HCID 57933432, compound

Procedure

Using general procedure D, rac-3-hydroxy-4-phenyl-cyclopent-2-enone (Lit. 17) was reacted with benzaldehyde and 5-fluoro-3-methyl-1H-indole to give the title compound as a red solid. MS: 412.0 ([M+H]+).

Sources & evidence

ORD record
ord-085a1d90ae8c49e6b107e92cf387d2da
Source dataset
uspto-grants-2009_11
Patent number
US07612099B2

Reaction notes

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