Potassium thiocyanate → HCID 87631551, compound

Participants

Reaction Steps

2.91 g of KSCN in 3 ml of H2O are added to a mixture of 5.96 g of 3,4-epoxy-N—(N-BOC-valyl-1,2,5,6-tetrahydropyridine in 10 ml of absolute EtOH and the mixture obtained is stirred for 72 hours at RT. The mixture obtained is subjected to aqueous extraction, the solvent of the organic phase obtained is evaporated and the evaporation residue is subjeted to chromatography. 3,4-Epithio-N(N-BOC-(R)-valyl)-piperidine is obtained. Melting point: 69.71°

Provenance & Evidence