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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 143266Generated: October 31, 2026

N-methyl-2-pyrrolidone → 4-chloro-3-fluoro-5-methyl-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-pyrrole-2-carboxylic acid

https://huagongshe.com/reaction/143266

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-methyl-2-pyrrolidoneHCID 13387—
Reactanttert-butyl 4-chloro-3-fluoro-5-methyl-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-pyrrole-2-carboxylateHCID 68516579—
Product4-chloro-3-fluoro-5-methyl-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-pyrrole-2-carboxylic acidHCID 68516085—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-8b7b38ae860441259f053fed7dba0263
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)