N-methyl-2-pyrrolidone → 4-chloro-3-fluoro-5-methyl-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-pyrrole-2-carboxylic acid
Reaction equation
[CH3:24][N:25]1[CH2:26][CH2:27][CH2:28][C:29]1=[O:30].[Cl:1][c:2]1[c:3]([F:23])[c:4]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[n:5]([CH2:8][O:9][CH2:10][CH2:11][Si:12]([CH3:13])([CH3:14])[CH3:15])[c:6]1[CH3:7]>>[Cl:1][c:2]1[c:3]([F:23])[c:4]([C:16](=[O:17])[OH:18])[n:5]([CH2:8][O:9][CH2:10][CH2:11][Si:12]([CH3:13])([CH3:14])[CH3:15])[c:6]1[CH3:7]Participants
3
Sources & evidence
- ORD record
- ord-8b7b38ae860441259f053fed7dba0263
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…