Pentamethylbenzene → HCID 69005603, compound

HRID 1432775Notes

Reaction equation

HRID 1432775 reaction equation
C([O:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]2[S:19][C:18]([C:20]([O:22][CH3:23])=[O:21])=[CH:17][CH:16]=2)=[CH:11][C:10]=1[C:24]#[N:25])C1C=CC=CC=1.CC1C(C)=C(C)C(C)=C(C)C=1>FC(F)(F)C(O)=O>[C:24]([C:10]1[CH:11]=[C:12]([C:15]2[S:19][C:18]([C:20]([O:22][CH3:23])=[O:21])=[CH:17][CH:16]=2)[CH:13]=[CH:14][C:9]=1[OH:8])#[N:25]

Participants

4

Reactant 2

HCID 12784PentamethylbenzeneHCID 69007683HCID 69007683, compound

Product 1

HCID 69005603HCID 69005603, compound

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

Methyl 5-[4-(benzyloxy)-3-cyanophenyl]thiophene-2-carboxylate and pentamethylbenzene were stirred at room temperature in trifluoroacetic acid to obtain methyl 5-(3-cyano-4-hydroxyphenyl)thiophene-2-carboxylate. F: 258.

Sources & evidence

ORD record
ord-e18574a92863430e80e0c1906af50302
Source dataset
uspto-grants-2009_11
Patent number
US07612108B2

Reaction notes

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