Chlorosuccinimide → HCID 69011823, compound
Reaction equation
[C:1]([C:3]1[CH:4]=[C:5]([C:10]2[S:14][C:13]([C:15]([O:17][CH3:18])=[O:16])=[CH:12][CH:11]=2)[CH:6]=[CH:7][C:8]=1[OH:9])#[N:2].[Cl:19]N1C(=O)CCC1=O>C(#N)C>[Cl:19][C:11]1[CH:12]=[C:13]([C:15]([O:17][CH3:18])=[O:16])[S:14][C:10]=1[C:5]1[CH:6]=[CH:7][C:8]([OH:9])=[C:3]([C:1]#[N:2])[CH:4]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
Methyl 5-(3-cyano-4-hydroxyphenyl)thiophene-2-carboxylate and N-chlorosuccinimide were stirred at room temperature in acetonitrile to obtain methyl 4-chloro-5-(3-cyano-4-hydroxyphenyl)thiophene-2-carboxylate. ESN: 292.
Sources & evidence
- ORD record
- ord-e9174fca0c3a450fa19dac721e4ab730
- Source dataset
- uspto-grants-2009_11
- Patent number
- US07612108B2
Reaction notes
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