HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 69007062, compound → HCID 69008032, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 69007062 | HCID 69007062 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | MeOH tetrahydrofuran | HCID 21899815 | — |
| Product | HCID 69008032 | HCID 69008032 | — |
Reaction Steps
Methyl 5-[4-(benzyloxy)-3-cyano-5-fluorophenyl]thiophene-2-carboxylate was stirred at room temperature in methanol-THF (1:1) under a hydrogen atmosphere at normal pressure in the presence of palladium-carbon to obtain methyl 5-(3-cyano-5-fluoro-4-hydroxyphenyl)thiophene-2-carboxylate. FN: 276.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07612108B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-d1339e59e04942d3ab16283c6b9654c1 |
| Source note | uspto-grants-2009_11 |