HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-[(5-Chlorothiophen-2-yl)oxy]acetic acid → HCID 54424585, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-[(5-Chlorothiophen-2-yl)oxy]acetic acid | HCID 11183144 | — |
| Reactant | 1-(4-Amino-quinazoline-7-ylmethyl)-3-methoxymethyl-6-methyl-piperazine-2-one | HCID 17985243 | — |
| Product | HCID 54424585 | HCID 54424585 | — |
Reaction Steps
The title compound is prepared as described in EXAMPLE 123 using 1-(4-amino-quinazoline-7-ylmethyl)-3-methoxymethyl-6-methyl-piperazine-2-one, EXAMPLE 87, and 5-chloro-2-thienyloxyacetic acid, EXAMPLE 24. 1H NMR (CD3OD300 MHz) δ8.68 (s, 1H), 8.27 (d, 1H), 7.62 (m, 2H), 6.54 (d, 1H), 6.18 (m, 1H), 7.39 (d, 1H), 4.94 (m, 4H), 4.15 (m, 2H), 3.76 (m, 2H), 3.44 (s, 3H), 3.10 (m, 2H), 1.28 (d, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07612075B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-bd1a8bcffe4d4e4ba7c2b43700f50b5a |
| Source note | uspto-grants-2009_11 |