HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → Temozolomide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | HCID 11658676 | HCID 11658676 | — |
| Solvent | Water | HCID 962 | — |
| Product | Temozolomide | HCID 5394 | — |
Reaction Steps
According to the present invention, the dissolution of Temozolomide hydrochloride in the mixture of acetic acid, acetonitrile, and water is complete (at pH range of 3-4), results in the precipitation of Temozolomide upon cooling.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07612202B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-73fd4603a2d447539955f29b9ce3c3ea |
| Source note | uspto-grants-2009_11 |