4-(Trifluoromethyl)phenol → HCID 178506219, compound

Participants

Reaction Steps

Using the procedure for Step E in Example 1, the title compound was prepared from 5-bromo-2-chloromethyl-1H-benzimidazole (200 mg, 0.816 mmol) and α,α,α-trifluoro-p-cresol (132 mg, 0.816 mmol) and was obtained as an off-white solid (76.2 mg, 25% yield). Calcd. For C21H16F3N3O3S: 371.15 (M+H), Found 371.0.

Provenance & Evidence