HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Bromomethyl)cyclobutane → (3S,5S)-3-(cyclobutylmethyl)-3-methyl-5-phenylmorpholin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (Bromomethyl)cyclobutane | HCID 2734658 | — |
| Reactant | (5S)-3-methyl-5-phenyl-5,6-dihydro-2H-1,4-oxazin-2-one | HCID 57467834 | — |
| Product | (3S,5S)-3-(cyclobutylmethyl)-3-methyl-5-phenylmorpholin-2-one | HCID 57467832 | — |
Reaction Steps
The title compound was prepared from (5S)-3-methyl-5-phenyl-5,6-dihydro-2H-1,4-oxazin-2-one (1 g, 5.28 mmol, see WO-A-02/051983) and (bromomethyl)cyclobutane according to the procedure outlined in Preparation 1. The total amount of compound synthesised was 0.445 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07612226B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-9cf3e34bd58e492b831420bab5ba832d |
| Source note | uspto-grants-2009_11 |