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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1433601Generated: October 31, 2026

HCID 22936266, compound → HCID 22936256, compound

https://huagongshe.com/reaction/1433601

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 22936266HCID 22936266—
SolventPyridineHCID 1049—
SolventAcetic AnhydrideHCID 7918—
ProductHCID 22936256HCID 2293625637.6%

Reaction Steps

After dissolving N-[4-(6-aminomethyl-7-methoxy-quinolin-4-yloxy)phenyl]-N′-phenylurea trifluoroacetate (40 mg) in pyridine (1.0 ml) and acetic anhydride (1.0 ml), the solution was stirred overnight at room temperature. The reaction solution was concentrated under reduced pressure and the obtained crude product was crystallized with ethyl acetate to obtain the title compound (13 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07612092B2
Source datasetuspto-grants-2009_11
ORD IDord-a5e119c14b874ebaaf87110b217e39c1
Source noteuspto-grants-2009_11