Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1433630Generated: November 1, 2026

Toluene → HCID 58931434, compound

https://huagongshe.com/reaction/1433630

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTolueneHCID 1140—
Reactant4-Fluorophenyl isocyanateHCID 70955—
ReactantHCID 58931477HCID 58931477—
SolventAcetonitrileHCID 6342—
ProductHCID 58931434HCID 58931434—

Reaction Steps

After adding toluene (1 ml), acetonitrile (0.5 ml) and 4-fluorophenyl isocyanate (0.03 ml) to 4-(6-phenyl-furo[2.3-d]pyrimidin-4-yloxy)phenylamine (40 mg), the mixture was heated to reflux for 30 minutes. After cooling, the precipitated crystals were filtered out and washed with toluene to obtain the title compound (42 mg) as light yellow crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07612092B2
Source datasetuspto-grants-2009_11
ORD IDord-2bc84d8656a34056ac09ec9668578625
Source noteuspto-grants-2009_11