Methylamine → HCID 22936859, compound

HRID 1433673Notes

Reaction equation

HRID 1433673 reaction equation
[C:1]([C:4]1[CH:5]=[C:6]2[C:11](=[CH:12][C:13]=1[O:14][CH3:15])[N:10]=[CH:9][CH:8]=[C:7]2[O:16][C:17]1[CH:22]=[CH:21][C:20]([NH:23][C:24](=[O:32])OC2C=CC=CC=2)=[C:19]([CH3:33])[C:18]=1[CH3:34])(=[O:3])[NH2:2].[CH3:35][NH2:36]>>[CH3:34][C:18]1[C:19]([CH3:33])=[C:20]([NH:23][C:24]([NH:36][CH3:35])=[O:32])[CH:21]=[CH:22][C:17]=1[O:16][C:7]1[C:6]2[C:11](=[CH:12][C:13]([O:14][CH3:15])=[C:4]([C:1]([NH2:2])=[O:3])[CH:5]=2)[N:10]=[CH:9][CH:8]=1

Participants

3

Reactant 2

HCID 6329MethylamineHCID 22936704HCID 22936704, compound

Product 1

HCID 22936859HCID 22936859, compound

Procedure

The title compound (30 mg) was obtained as colorless crystals from phenyl N-(4-(6-carbamoyl-7-methoxy-4-quinolyl)oxy-2,3-dimethyl phenyl)carbamate) (56 mg) and methylamine (2M tetrahydrofuran solution), by the same procedure as in Example 11.

Sources & evidence

ORD record
ord-45fd1217057b4b9997be3d49bd3ea64d
Source dataset
uspto-grants-2009_11
Patent number
US07612092B2

Reaction notes

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