HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 58930988, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Glycidyl tosylate, (R)- | HCID 154187 | — |
| Reactant | 4-[3-Chloro-4-(cyclopropylcarbamamido)phenoxy]-7-hydroxy-6-quinolinecarboxamide | HCID 135566046 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 58930988 | HCID 58930988 | — |
Reaction Steps
After adding (2R)oxiran-2-ylmethyl 4-methyl-1-benzenesulfonate (308 mg, 1.35 mmol), potassium carbonate (149 mg, 1.08 mmol) and dimethylformamide (9 ml) to 4-(3-chloro-4-(((cyclopropylamino)carbonyl)amino)phenoxy)-7-hydroxy-6-quinolinecarboxamide (372.0 mg, 0.90 mmol),
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07612092B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-9765dd882fa54b2fb024c34092bffdd3 |
| Source note | uspto-grants-2009_11 |