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HRID1433789

反应详情

EQUATION

反应方程式

HRID 1433789 的结构方程式

REACTANTS

反应物

4
结构：C[C@@H](c1ccccc1)[C@H](NC(=O)OC(C)(C)C)C(=O)O
HCID7021178

未命名化合物

结构：C[C@@H](OCc1ccccc1)[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O
HCID16213170

O-Benzyl-N-{[(9H-fluoren-9-yl)methoxy]carbonyl}-L-threonine

C26H25NO5

结构：CC(C)(C)OC(=O)N[C@@H](C(=O)O)c1ccc(OC[C@H]2COC(C)(C)O2)cc1
HCID67001404

未命名化合物

结构：C[C@@H](c1ccccc1)[C@H](NC(=O)[C@H](N)c1ccc(OC[C@H](O)CO)cc1)C(=O)Nc1ccc(I)cc1Cl
HCID69006543

未命名化合物

PRODUCTS

生成物

1
结构：COCCOc1ccc([C@@H](NC(=O)OC(C)(C)C)C(=O)O)cc1
HCID66815175

未命名化合物

PROCEDURE

实验过程

Prepared by the same method as described in example 3 except that (i) 2-chloro-4-iodoaniline was used in place of 4-bromo-2-chloroaniline in step 1, (ii) (2S,3S)-2-tert-butoxycarbonylamino-3-methyl-pentanoic acid was used in place (2S,3S)-2-tert-butoxycarbonylamino-3-phenyl-butyric acid in step 1, and (iii) (R)-tert-butoxycarbonylamino-[4-(2-methoxy-ethoxy)-phenyl]-acetic acid was used in place of (R)-tert-butoxycarbonylamino-[4-(2-tert-butoxy-ethoxy)-phenyl]-acetic acid in step 2. (R)-tert-Butoxycarbonylamino-[4-(2-methoxy-ethoxy)-phenyl]-acetic acid was prepared as described in example 80.

WORKUP

后处理

  1. customPrepared by the same method