Resorcinol → 2-hydroxy-4-methoxy-3'-methoxy-benzophenone

HRID 1434422Notes

Reaction equation

HRID 1434422 reaction equation
[C:1]1(C=CC=C(O)C=1)O.COC1C=C(C=CC=1)C(Cl)=O.[OH:20][C:21]1[CH:26]=[C:25]([OH:27])[CH:24]=[CH:23][C:22]=1[C:28]([C:30]1[CH:35]=[CH:34][CH:33]=[C:32]([O:36][CH3:37])[CH:31]=1)=[O:29].CI>>[OH:20][C:21]1[CH:26]=[C:25]([O:27][CH3:1])[CH:24]=[CH:23][C:22]=1[C:28]([C:30]1[CH:35]=[CH:34][CH:33]=[C:32]([O:36][CH3:37])[CH:31]=1)=[O:29]

Participants

5

Reactant 4

HCID 5054ResorcinolHCID 6328Methyl iodideHCID 74374m-Anisoyl chlorideHCID 11322504HCID 11322504, compound

Product 1

HCID 113228592-hydroxy-4-methoxy-3'-methoxy-benzophenone

Procedure

Synthesized from resorcinol and 3-methoxybenzoyl chloride according to an analogous synthetic method to Preparation Example 66, (2,4-dihydroxyphenyl)(3-methoxyphenyl)methanone (14.7 g) and methyl iodide (9.4 g) were used according to an analogous synthetic method to Example 383 to provide the title compound (10.3 g).

Sources & evidence

ORD record
ord-41fa146bb00f45668e9b523d3144ad8f
Source dataset
uspto-grants-2009_11
Patent number
US07612114B2

Reaction notes

Loading…