Phenol → HCID 22020084, compound

HRID 1434498Notes

Reaction equation

HRID 1434498 reaction equation
[Br:1][C:2]1[CH:14]=[CH:13][C:12]2[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[CH2:5][C:4]=2[CH:3]=1.CS(O)(=O)=O.[C:20]1([OH:26])[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>O>[Br:1][C:2]1[CH:14]=[CH:13][C:12]2[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5]([C:23]3[CH:24]=[CH:25][C:20]([OH:26])=[CH:21][CH:22]=3)([C:23]3[CH:24]=[CH:25][C:20]([OH:26])=[CH:21][CH:22]=3)[C:4]=2[CH:3]=1

Participants

5

Reactant 3

HCID 996PhenolHCID 6395Methanesulfonic AcidHCID 143362-Bromo-9H-fluorene

Product 1

HCID 22020084HCID 22020084, compoundYield 68.5%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
150 °C

Procedure

10 g of 2-bromofluorene, 2 equivalents of methane sulfonic acid and 100 g of phenol were placed into a 500 ml round-bottom flask, followed by stirring at 150° C. for 24 hours. The reaction solution was cooled and then mixed with water to filter solids. The solids were then recrystallized in toluene, to yield 12 g of (2-bromo-9,9-di(4-hydroxyphenyl)fluorene) (5).

Workup

  1. temperatureThe reaction solution was cooled
  2. filtrationto filter solids
  3. customThe solids were then recrystallized in toluene

Sources & evidence

ORD record
ord-6242b196ef9d42e298b280cd776077b9
Source dataset
uspto-grants-2009_11
Patent number
US07615289B2

Reaction notes

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