HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86605953, compound → HCID 69073210, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86605953 | HCID 86605953 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 69073210 | HCID 69073210 | — |
Reaction Steps
260 mg (0.6 mmol) benzyl (R)-{1-[2-fluoro-4-(3-oxo-morpholin-4-yl)-phenyl]-5-oxo-pyrrolidin-3-yl}-carbamate are dissolved in 10 ml of methanol, combined with 180 mg palladium on charcoal and hydrogenated for 3.75 hours in a Parr apparatus at 3 bar hydrogen pressure at ambient temperature.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07615549B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-82417a3014224818bae741bff36b9200 |
| Source note | uspto-grants-2009_11 |