HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 69052229, compound → HCID 69057404, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 69052229 | HCID 69052229 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 69057404 | HCID 69057404 | — |
Reaction Steps
1.95 g (7.79 mmol) 3-(2-methyl-4-nitro-phenyl)-[1,3]oxazepan-2-one are dissolved in 200 ml of tetrahydrofuran and combined with 700 mg Raney nickel. The mixture is hydrogenated in a Parr apparatus at ambient temperature at 1 bar hydrogen pressure for four hours. Then the catalyst is filtered off and the filtrate is evaporated down i. vac.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07615549B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-51e22662421c45bd8a4f3273aa83b56a |
| Source note | uspto-grants-2009_11 |