4-[4-(3-Piperidin-1-yl-propoxy)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester → 1-[4-(3-Piperidin-1-ylpropoxy)phenyl]piperazine

Participants

Reaction Steps

A solution of 4-[4-(3-piperidin-1-yl-propoxy)phenyl]-piperazine-1-carboxylic acid tert-butyl ester (D10) (1.0 g; 2.48 mM) in trifluoroacetic acid (5 ml) was stirred at room temperature for 60 minutes. The resulting mixture was purified on an SCX ion exchange cartridge to afford the title compound as a colourless crystalline solid (0.76 g)

Provenance & Evidence