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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1434571Generated: October 31, 2026

tert-Butyl 4-(3-hydroxyphenyl)piperazine-1-carboxylate → 4-[3-(3-Chloro-propoxy)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/1434571

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl 4-(3-hydroxyphenyl)piperazine-1-carboxylateHCID 18669061—
Reactant4-[4-(3-Chloro-propoxy)-phenyl]-piperazine-1-carboxylic acid tert-butyl esterHCID 58817843—
Product4-[3-(3-Chloro-propoxy)-phenyl]-piperazine-1-carboxylic acid tert-butyl esterHCID 68699812—

Reaction Steps

Prepared from 4-(3-hydroxy-phenyl)-piperazine-1-carboxylic acid tert-butyl ester (D12) using the same method described in Description 9 (D9).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07615550B2
Source datasetuspto-grants-2009_11
ORD IDord-7c697bfc38044029832253a8cdee4d57
Source noteuspto-grants-2009_11