HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[4-(3-Piperidin-1-yl-propoxy)-benzyl]-[1,4]diazepane → Phenyl[4-({4-[(piperidin-4-yl)oxy]phenyl}methyl)piperazin-1-yl]methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[4-(3-Piperidin-1-yl-propoxy)-benzyl]-[1,4]diazepane | HCID 59640592 | — |
| Reactant | 4-{4-[4-(1-Phenyl-methanoyl)-piperazin-1-ylmethyl]-phenoxy}-piperidine-1-carboxylic acid tert-butyl ester | HCID 68702123 | — |
| Product | Phenyl[4-({4-[(piperidin-4-yl)oxy]phenyl}methyl)piperazin-1-yl]methanone | HCID 57935703 | — |
Reaction Steps
The title compound (E32) was prepared from 4-{4-[4-(1-phenyl-methanoyl)-piperazin-1-ylmethyl]-phenoxy}-piperidine-1-carboxylic acid tert-butyl ester (D7) using the method described in Description 4 (D4). MS(ES+) m/e 380 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07615550B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-b147f8fac206488cbd72ad7fdf553214 |
| Source note | uspto-grants-2009_11 |