HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl 4-(2-oxoimidazolidin-1-yl)piperidine-1-carboxylate → 1-(Piperidin-4-yl)imidazolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl 4-(2-oxoimidazolidin-1-yl)piperidine-1-carboxylate | HCID 23463818 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-(Piperidin-4-yl)imidazolidin-2-one | HCID 13031757 | — |
Reaction Steps
A solution of benzyl 4-(2-oxoimidazolidin-1-yl)piperidine-1-carboxylate (3.2 g) in ethanol (200 ml) was hydrogenated under a hydrogen filled balloon with 20% palladium on charcoal as catalyst. The catalyst was filtered and the filtrate evaporated to dryness to give the title compound as a white solid, yield 1.6 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07615555B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-26da20d065b84c89b7c4bff88de12523 |
| Source note | uspto-grants-2009_11 |