4-tert-Butylbenzylamine → HCID 178440915, compound

Participants

Reaction Steps

The title compound was prepared by reacting the product of Example 1B (0.1507 g, 0.51 mmol) with 4-tert-butylbenzylamine (0.1070 g, 0.66 mmol) using the procedure as described in Example 1C. MS (ESI+) m/z 440 (M+H)+; (ESI−) m/z 438 (M−H)−; 1H NMR (300 MHz, CDCl3) δ 1.33 (s, 9H), 4.79 (d, J=5.4 Hz, 2H), 6.14 (t, J=5.3 Hz, 1H), 7.32 (dd, J=8.0, 4.6 Hz, 1H), 7.37 (m, 2H), 7.44 (m, 2H), 7.57 (d, J=8.1 Hz, 1H), 7.85 (dd, J=8.1, 1.4 Hz, 1H), 8.03 (dd, J=8.1, 1.4 Hz, 1H), 8.34 (d, J=1.0 Hz, 1H), 8.62 (dd, J=4.4, 1.4 Hz, 1H).

Provenance & Evidence