Hydrochloric Acid → {5-[2-(4-Acetylamino-phenylsulfanyl)-5-methyl-phenylamino]-[1,8]naphthyridin-2-ylamino}-acetic acid ethyl ester

HRID 143481Notes

Reaction equation

HRID 143481 reaction equation
[CH2:32]([CH3:33])[O:34][C:35]([CH2:36][NH2:37])=[O:38].[CH3:39][CH2:40][OH:41].[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([NH:12][c:13]3[c:14]([S:20][c:21]4[cH:22][cH:23][c:24]([NH:27][C:28]([CH3:29])=[O:30])[cH:25][cH:26]4)[cH:15][cH:16][c:17]([CH3:19])[cH:18]3)[cH:7][cH:8][n:9][c:10]2[n:11]1.[ClH:31]>>[c:2]1([NH:37][CH2:36][C:35]([O:34][CH2:32][CH3:33])=[O:38])[cH:3][cH:4][c:5]2[c:6]([NH:12][c:13]3[c:14]([S:20][c:21]4[cH:22][cH:23][c:24]([NH:27][C:28]([CH3:29])=[O:30])[cH:25][cH:26]4)[cH:15][cH:16][c:17]([CH3:19])[cH:18]3)[cH:7][cH:8][n:9][c:10]2[n:11]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 702EthanolHCID 12176Glycine ethyl esterHCID 86615485N-{4-[2-(7-Chloro-[1,8]naphthyridin-4-ylamino)-4-methyl-phenylsulfanyl]-phenyl}-acetamide

Product 1

HCID 68461945{5-[2-(4-Acetylamino-phenylsulfanyl)-5-methyl-phenylamino]-[1,8]naphthyridin-2-ylamino}-acetic acid ethyl ester

Sources & evidence

ORD record
ord-b27eb85a09644ce28f8457e2e5126554
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…