Methyl iodide → HCID 57936564, compound

HRID 1434862Notes

Reaction equation

HRID 1434862 reaction equation
[CH:1]([Si:4]([O:11][CH2:12][CH:13]([OH:23])[CH2:14][NH:15][C:16]([O:18][C:19]([CH3:22])([CH3:21])[CH3:20])=[O:17])([CH:8]([CH3:10])[CH3:9])[CH:5]([CH3:7])[CH3:6])([CH3:3])[CH3:2].[CH3:24]I>>[CH:8]([Si:4]([O:11][CH2:12][CH:13]([O:23][CH3:24])[CH2:14][NH:15][C:16]([O:18][C:19]([CH3:22])([CH3:21])[CH3:20])=[O:17])([CH:5]([CH3:7])[CH3:6])[CH:1]([CH3:3])[CH3:2])([CH3:9])[CH3:10]

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 579366063-(t-Butoxycarbonylamino)-2-hydroxypropyl Triisopropylsilyl Ether

Product 1

HCID 57936564HCID 57936564, compoundYield 62%

Procedure

Using a procedure analogous to Example 57-B, 3-(t-butoxycarbonylamino)-2-hydroxypropyl triisopropylsilyl ether and methyl iodide gave the title compound (13 g, 62%).

Sources & evidence

ORD record
ord-d4197aed26de4ca885f5552edc3b8199
Source dataset
uspto-grants-2009_11
Patent number
US07615568B2

Reaction notes

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