Cyanamide → HCID 178508317, compound

Participants

Reaction Steps

In another embodiment of the invention, a method of synthesizing N,N-didesmethylgrossularine-1 2 is described comprising: condensing oxotryptamine 3 and cyanamide in the absence of air to produce 2-amino-4-(3-indolyl)imidazole 6; exposing 2-amino-4-(3-indolyl)imidazole 6 to an ammonia saturated methanol solution in air to produce imine 10; and exposing imine 10 to hydrolosis conditions to produce N,N-didesmethylgrossularine-1 2.

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