4-Amino-2,2,6,6-tetramethylpiperidine → HCID 11224151, compound

HRID 1434931Notes

Reaction equation

HRID 1434931 reaction equation
[CH3:1][C:2]([CH3:13])([CH2:7][C:8]1[S:9][CH:10]=[CH:11][CH:12]=1)[C:3]([NH:5][CH3:6])=[O:4].Cl[C:15]1[N:20]=[C:19](Cl)[CH:18]=[CH:17][N:16]=1.[CH3:22][C:23]1([CH3:32])[CH2:28][CH:27]([NH2:29])[CH2:26][C:25]([CH3:31])([CH3:30])[NH:24]1>>[CH3:1][C:2]([CH3:13])([CH2:7][C:8]1[S:9][C:10]([C:17]2[CH:18]=[CH:19][N:20]=[C:15]([NH:29][CH:27]3[CH2:28][C:23]([CH3:32])([CH3:22])[NH:24][C:25]([CH3:31])([CH3:30])[CH2:26]3)[N:16]=2)=[CH:11][CH:12]=1)[C:3]([NH:5][CH3:6])=[O:4]

Participants

4

Reactant 3

HCID 375244-Amino-2,2,6,6-tetramethylpiperidineHCID 775312,4-DichloropyrimidineHCID 57936326HCID 57936326, compound

Product 1

HCID 11224151HCID 11224151, compound

Procedure

The title compound was prepared analogous to Steps B and C of Method A, starting from 2,2,N-trimethyl-3-thiophen-2-yl-propionamide, 2,4-dichloro-pyrimidine and 2,2,6,6-tetramethyl-piperidin-4-ylamine.

Sources & evidence

ORD record
ord-b88e0f6dce99431a8e11e8113984b5bf
Source dataset
uspto-grants-2009_11
Patent number
US07615562B2

Reaction notes

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