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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1434938Generated: November 2, 2026

(4-Chloro-pyrimidin-2-yl)(2,2,6,6-tetramethyl-piperidin-4-yl)-amine → HCID 11430421, compound

https://huagongshe.com/reaction/1434938

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Chloro-pyrimidin-2-yl)(2,2,6,6-tetramethyl-piperidin-4-yl)-amineHCID 57936167—
ReactantHCID 69068728HCID 69068728—
ProductHCID 11430421HCID 11430421—

Reaction Steps

The title compound was prepared analogous to Method C, starting from (4-chloro-pyrimidin-2-yl)-(2,2,6,6-tetramethyl-piperidin-4-yl)-amine and 4-(3-methoxy-thiophen-2-yl)-2-methyl-butan-2-ol (prepared by Pd/C hydrogenation of (E)-3-(3-Methoxy-thiophen-2-yl)-acrylic acid methyl ester, followed by reaction with MeMgBr (Step A of Method A)).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07615562B2
Source datasetuspto-grants-2009_11
ORD IDord-36f0c9e4abd44bef82093604e08f1442
Source noteuspto-grants-2009_11