HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 11292158, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | (4-Chloro-pyrimidin-2-yl)(2,2,6,6-tetramethyl-piperidin-4-yl)-amine | HCID 57936167 | — |
| Reactant | HCID 69065499 | HCID 69065499 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 11292158 | HCID 11292158 | — |
Reaction Steps
The title compound was prepared analogous to Method C, starting from (4-chloro-pyrimidin-2-yl)-(2,2,6,6-tetramethyl-piperidin-4-yl)-amine and (1,1-Dimethyl-2-thiophen-2-yl-ethyl)-carbamic acid tert-butyl ester (prepared by BOC protection of 1,1-Dimethyl-2-thiophen-2-yl-ethylamine), followed by BOC cleavage with HCl in dioxane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07615562B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-0269310b9ffd4a18be7df966745895b9 |
| Source note | uspto-grants-2009_11 |