Hydrochloric Acid → HCID 57936176, compound

Participants

Reaction Steps

5-[2-(2,2,6,6-Tetramethyl-piperidin-4-ylamino)-pyrimidin-4-yl]-thiophene-2-carboxylic acid ethyl ester (4.90 g, 12.6 mmol) were dissolved in methanol (50 ml). After addition of sodium hydroxide (31 ml of a 40% solution) the mixture was stirred at room temperature overnight. The reaction mixture was acidified using 1N HCl and the product was collected by filtration (4.50 g, 12.5 mmol).

Provenance & Evidence