HCID 57936256, compound → HCID 57936259, compound

Participants

Reaction Steps

Compound of Example 149 (4.0 g, 10.0 mmol) was dissolved in 100 ml of EtOH and hydrogenated in the presence of 200 mg palladium on charcoal 10% at room temperature and 1 bar for 5 hours. Then the mixture was filtered through Hyflo and evaporated. The crude was purified by chromatography on silicagel (DCM/MeOH/ammonia:8/2/0.2). Yield: 2.76 g (89%).

Provenance & Evidence